Diagnostic and Predictive Genetic Testing in Psychiatry: Potential and Pitfalls
Chair: J. Raymond DePaulo, Co-Chair: Peter Schofield

1. HOW DO PATIENTS RESPOND TO RECEIPT OF RESULTS FOR A PSYCHIATRIC GENETIC TEST? Phil Mitchell
2. COMMUNICATING WITH AFFECTED INDIVIDUALS AND THEIR FAMILIES ABOUT PSYCHIATRIC GENETIC TESTS, Jehannine Austin
3. ATTITUDES TOWARD GENETIC TESTING AMONG SCHIZOPHRENIA-SPECTRUM PATIENTS AND FIRST-DEGREE RELATIVES, Jinger Hoop
4. COMMUNITY INTEREST IN PREDICTIVE GENETIC TESTING FORSUSCEPTIBILITY TO MAJOR DEPRESSION IN A LARGE NATIONAL SAMPLE, Alex Wilde

S4: Genome-Wide Association Studies on Major Depression: What’s Next? (Salon F )
Chair: Witte Hoogendijk, Co-Chair: Marianna Bevova

1. GENOME-WIDE ASSOCIATION STUDIES IN MAJOR DEPRESSION. THE ROLE OF ENDOPHENOTYPES, Witte Hoogendijk
2. GENOME-WIDE ANALYSIS IN MAJOR DEPRESSION - AND NOW? Bertram Müller-Myhsok
3. MICE THEN HUMANS: A COMPLEMENTARY APPROACH TO DISSECTING THE BIOLOGY OF MDD, Patrick Sullivan
4. GENOME-WIDE PREDICTION OF FUNCTIONAL GENE-GENE INTERACTIONS FOR DEPRESSION, Zoltán Bochdanovits
5. DISCOVERY AND TESTING OF DELETIONS FOR ASSOCIATION WITH MDD IN GAIN STUDY, Marianna Bevova

S5: New Insights from Studies of Rare Structural Variation in Psychiatric Disorders (Salon G)
Chair: Jonathan Sebat, Co-Chair: Elliot Gershon

1. SCHIZOPHRENIA: A COMMON DISEASE DUE TO MULTIPLE RARE ALLELES? Jack McClellan
2. DELETIONS IN NRXN1 IN SCHIZOPHRENIA, George Kirov
3. VERY RARE CNVS ASSOCIATED WITH BIPOLAR DISORDER, Elliot Gershon
4. FROM CNV “HOT SPOTS” TO THE REST OF THE GENOME, LOOKING BEYOND THE LOW LYING FRUIT, Jonathan Sebat
5. ANALYSIS OF RARE STRUCTURAL VARIANTS IN BIPOLAR DISORDER AND SCHIZOPHRENIA, Shaun Purcell

S6: Psychiatric Disorder Biomarkers (Salon H)
Chair: Chris Turck, Co-Chair: Alexander Niculescu

1. THE QUEST FOR PSYCHIATRIC DISORDER BIOMARKERS: FROM DIFFERENTIAL EXPRESSION TO ISOFORMS TO PATHWAYS, Chris Turck
2. BIOMARKER DISCOVERY IN SCHIZOPHRENIA AND BIPOLAR DISORDER: TRANSCRIPTOMIC, SPLICEOMIC, AND PATHWAY ANALYSIS FINDINGS, Stephen Glatt
3. IDENTIFICATION OF BLOOD BIOMARKERS FOR PSYCHOSIS USING CONVERGENT FUNCTIONAL GENOMICS, Alexander B. Niculescu
4. UNDERSTANDING MENTAL ILLNESS THROUGH PERIPHERAL BIOMARKER STUDIES, Melvin McInnis
5. EXON ARRAY FINDINGS IN LYMPHOBLASTIC CELL LINES IN SCHIZOPHRENIA, Marquis Vawter

S7: Small RNA in Neuropsychiatry (Salon F)
Chair: Gerome Breen, Co-Chair: Murray Cairns

1. BIOINFORMATIC ANALYSIS OF POTENTIAL MIRNA INVOLVEMENT IN PSYCHIATRIC DISEASE, Sarah Jugurnauth
2. ALTERATION OF CORTICAL MICRORNA BIOGENESIS IN SCHIZOPHRENIA AND ITS INFLUENCE ON GENE EXPRESSION, Murray Cairns
3. ALTERATION OF THE GENE REGULATORY NETWORK IN THE FRONTAL CORTEX OF HIV-INFECTED INDIVIDUALS, Erick Tatro
4. MICRORNAS IN THE TRANSITION FROM CONTROLLED TO COMPULSIVE COCAINE-TAKING, Paul Kenny

S8: Attention Deficit Hyperactivity Disorder: Environmental Influences on the Genome (Salon G)
Chair: Stephen Faraone, Co-Chair: James Hudziak

1. 2009 Richard Todd Award Lecture
   WHOLE GENOME METHYLATION STUDY OF 48 MONOZYTGOTIC PAIRS CONCORDANT OR DISCORDANT FOR ATTENTION PROBLEMS, Robert Althoff
2. THE DEVELOPMENTAL COURSE OF GENE EXPRESSION IN BRAINS OF RATS PRENATALLY EXPOSED TO POLYCHLORINATED BIPHENYLS, Tania DasBanerjee
3. A PILOT STUDY OF METHYLATION IN ADHD YOUTH PRENATALLY EXPOSED TO CIGARETTE SMOKE, Stephen Faraone
4. JOINT EFFECTS OF TOXIN EXPOSURES AND RISK GENOTYPES ON ADHD SYMPTOMS, Joel Nigg

S9: Beyond Genome-Wide Association Studies (GWAS): Extending the Phenotype (Salon H)
Chair: Anil Malhotra, Co-Chair: Katherine Burdick

1. USING NEUROPSYCHOLOGICAL AND IMAGING PHENOTYPES TO INVESTIGATE THE FUNCTION OF GWAS IDENTIFIED RISK VARIANTS: NOS1 AND COGNITION, Gary Donohoe
2. USING NEUROCOGNITION AS AN ENDOPHENOTYPE IN A GWAS DATASET, Katherine Burdick
3. PHARMACOGENETIC APPROACHES IN A GENOME-WIDE DATASET, Anil Malhotra
4. ALTERNATIVE PHENOTYPES IN BIPOLAR DISORDER: DOES UNDERLYING GENETIC ARCHITECTURE MAP ONTO CLINICAL FEATURES? John Kelsoe

1. COPY NUMBER VARIATION AT 15Q11.2 ARE ASSOCIATED WITH BIPOLAR DISORDER AND MAJOR DEPRESSION IN CHINESE HAN POPULATION, YongYong Shi
2. GENETICS OF DIURNAL CORTISOL SECRETION: A GENOME WIDE ASSOCIATION STUDY, Fleur Velders
3. CRY2 IS A KEY TO DEPRESSION, Louise Sjöholm
4. GENOME-WIDE ASSOCIATION STUDY OF UNIPOLAR DEPRESSION IN THE UK POPULATION, Cathryn Lewis
5. GWAS ASSOCIATION STUDY OF CIRCADIAN GENES SUPPORTS ARNTL AS A MORNINGNESS-EVENINGNESS LOCUS, Caroline Nievergelt
6. GENOME-WIDE ASSOCIATION STUDY OF TEMPERAMENT AS AN INTERMEDIATE PHENOTYPE FOR BIPOLAR DISORDER, Tiffany Greenwood

O8: Schizophrenia 2 (Salon G)
Chair: Douglas Levinson, Co-Chair: Ming Tsuang

1. MATERNAL HSV2 INFECTION INTERACTS WITH NMDA GENE POLYMORPHISMS IN THE OFFSPRING INFLUENCING THE RISK OF SCHIZOPHRENIA, Ditte Demontis
2. EXON-BASED RE-SEQUENCING ANALYSIS OF THE SCHIZOPHRENIA SUSCEPTIBILITY GENE NRXN1,Thomas W. Mühleisen
3. GENOME-WIDE ASSOCIATION STUDY OF REGIONAL BRAIN VOLUME IN 600 INDIVIDUALS SUGGESTS INVOLVEMENT OF KNOWN PSYCHIATRY CANDIDATE GENES, IDENTIFIES NEW CANDIDATES FOR PSYCHIATRIC DISORDERS AND POINTS TO POTENTIAL MODES OF THEIR ACTION, Barbara Franke
4. ASSOCIATION OF A FUNCTIONAL HAPLOTYPE OF THE POST-SYNAPTIC DENSITY 95 (PSD-95) GENE WITH SCHIZOPHRENIA, Chia-Hsiang Chen
5. GENOME-WIDE ASSOCIATION STUDY (GWAS) OF SCHIZOPHRENIA IN A LARGE GENETICALLY HOMOGENEOUS IRISH POPULATION, The Schizophrenia Genomics Ireland Consortium
6. ZNF804A: SCHIZOPHRENIA RISK ALLELE ASSOCIATED WITH NEUROANATOMIC, COGNITIVE, AND CLINICAL PHENOTYPES, Todd Lencz

O9: Early Career Investigator – Candidate Genes, Epigenetics and Phenomics (Salon H)
Chair: Thomas Schulze, Co-Chair: Catharina Lavebratt

1. THE VAL 158 MET POLYMORPHISM IN THE COMT GENE IS ASSOCIATED WITH DEPRESSION AND MOTIVATION, Elin Aberg
2. RE-SEQUENCING ANALYSIS OF THE SCHIZOPHRENIA-ASSOCIATED MICRODELETION REGION ON 1Q21.1, Finat Buket Basmanav
3. FAMILIAL FORMS OF PSYCHIATRIC DISORDERS IN A LARGE, NATIONALLY REPRESENTATIVE SAMPLE, Nancy Low
4. RESPONSE TO LITHIUM IN BIPOLAR DISORDER: INTER-RATER RELIABILITY AND DISTRIBUTIONAL PROPERTIES, Mirko Manchia
5. PROFILING EPIGENETIC CHANGES IN THE BRAIN ASSOCIATED WITH SCHIZOPHRENIA, BIPOLAR DISORDER, AND MAJOR DEPRESSIVE DISORDER, Ruth Pidsley
6. DIRAS2 IS ASSOCIATED WITH ADULT ADHD AND RELATED PERSONALITY TRAITS, Andreas Reif
7. A LONGITUDINAL STUDY OF EPIGENETIC VARIATION IN TWINS, Chloe Chung Wong
8. INTERACTION BETWEEN CRHR1 GENE AND CHILDHOOD TRAUMA PREDICTS ADOLESCENT DEPRESSIVE AND ANXIETY SYMPTOMS, Kirstin Thode