P3: Plenary Session
Chair: Martin Schalling, Co-Chair: Lynn DeLisi

P3.1: EPIGENETIC APPROACHES TO COMMON DISEASE, Andrew Feinberg

STRUCTURAL VARIATION IN THE GENOME: A WINDOW INTO THE UNDERLYING CAUSES OF BRAIN DISORDERS, Jonathan Sebat

S10: Obsessive Compulsive Disorder and Tourette Disorder: Phenotype, Genotype and Genome-Wide Association Studies (Salon F)
Chair: David Pauls, Co-Chair: Danielle Cath

1. OBSESSIVE COMPULSIVE DISORDER AND TOURETTE DISORDER: PHENOTYPE, GENOTYPE AND GENOME-WIDE ASSOCIATION STUDIES, David Pauls
2. LATENT STRUCTURE IN OBSESSIVE COMPULSIVE DISORDER, Carol Mathews
3. GENOME-WIDE ASSOCIATION STUDY OF TOURETTE DISORDER IN EUROPEAN ANCESTRY SAMPLES AND FOUR POPULATION ISOLATES, Jeremiah Scharf
4. A GENOME-WIDE ASSOCIATION STUDY OF OBSESSIVE-COMPULSIVE DISORDER, S. Evelyn Stewart
5. DLGAP3 AND OBSESSIVE-COMPULSIVE DISORDER, Paul Arnold
6. GENOME-WIDE LINKAGE ANALYSES OF COSTA RICAN FAMILIES WITH OBSESSIVE COMPULSIVE DISORDER, Jessica Ross
7. TIC SYMPTOM DIMENSIONS AND THEIR HERITABILITY IN TOURETTE’S SYNDROME, Danielle Cath

S11: Pharmacogenetics of Psychiatric Treatments – Are We Ready for the Clinic? (Salon G)
Chair: Vicki Ellingrod

1. PHARMACOGENETICS OF ATYPICAL ANTIPSYCHOTIC EXPOSURE, FOLATE METABOLISM, CARDIOVASCULAR DISEASE, AND ENDOTHELIAL FUNCTIONING, Vicki Ellingrod
2. VARIANTS OF ABC TRANSPORTERS: CURRENT RELEVANCE IN PSYCHIATRY, Lindsay DeVane
3. PHARMACOGENETICS OF SSRI ASSOCIATED SEXUAL DYSFUNCTION AND MEDICATION INTOLERANCE, Jeffrey Bishop
4. VARIANTS OF THE SEROTONIN SYSTEM AND BONE MINERALIZATION IN BOYS TREATED WITH SELECTIVE SEROTONIN REUPTAKE INHIBITORS, Chadi Calarge
5. CYP450 GENOTYPING IN THE CLINICAL USE OF ANTIPSYCHOTIC AND ANTIDEPRESSANT DRUG TREATMENT, Daniel J. Müller

S12: Understanding Normal Variation in Brain Structure and Function Will Inform Psychiatric Genetics (Salon H)
Chair: Laura Almasy, Co-Chair: David Glahn

1. HERITABILITY OF FMRI RESPONSE IN YOUNG ADULT TWINS, Nick Martin
2. GENETIC ANALYSIS FOR NORMAL VARIATION IN COGNITION, SLEEP AND SEASONAL RHYTHMS: EXPERIENCES FROM TWIN AND POPULATION-BASED STUDIES FROM FINLAND, Tiina Paunio
3. A GENETIC INVESTIGATION OF SCHIZOPHRENIA ENDOPHENOTYPES IN A NEPALESE POPULATION GENETIC ISOLATE, Susan Santangelo
4. GENOME-WIDE COMBINED LINKAGE/ASSOCIATION SCAN LOCALIZES TWO QTLS INFLUENCING HUMAN CAUDATE NUCLEUS VOLUME, David Glahn
5. GENOMIC AND TRANSCRIPTOMIC APPROACHES TO IDENTIFYING GENES INFLUENCING COGNITION AND NEUROANATOMY, Laura Almasy

S13: Anorexia Nervosa – Genes or Jeans (Salon F)
Chair: Pierre Magistretti, Co-Chair: Walter Kaye

1. A GENOME-WIDE ASSOCIATION STUDY IN PATIENTS WITH ANOREXIA NERVOSA, Kai Wang
2. GENOME-WIDE ASSOCIATION OF PERSONALITY TRAITS IN INDIVIDUALS WITH ANOREXIA NERVOSA, Cinnamon Bloss
3. GENETICALLY MEDIATED, PRE-MORBID VULNERABILITIES OF TEMPERAMENT AND PERSONALITY IN ANOREXIA AND BULIMIA NERVOSA, Walter Kaye
4. THE PRICE FOUNDATION STUDIES – A RESOURCE FOR ANOREXIA NERVOSA RESEARCH, Andrew Bergen
5. LARGE-SCALE CANDIDATE GENE RESEQUENCING IN ANOREXIA NERVOSA, Ashley Scott

O10: Mood Disorders 3 (Salon G)
Chair: Douglas Blackwood, Co-Chair: Steve Hamilton

1. ASSOCIATION BETWEEN DISTRACTIBILITY AND P2RX7 IN SWEDISH BIPOLAR DISORDER PATIENTS, Lena Backlund
2. THE INTERACTION BETWEEN SEROTONIN TRANSPORTER GENE (SLC6A4) SINGLE NUCLEOTIDE POLYMORPHISMS (SNPS) AND DEPRESSION RISK FACTORS, Zainab Samaan
3. GABAA RECEPTOR GENE VARIATION AND SCHIZOAFFECTIVE DISORDER, BIPOLAR TYPE: EVIDENCE IMPLICATING GABRR1, Elaine Green
4. IDENTIFYING PANELS OF GENES FOR GENETIC RISK PREDICTION IN BIPOLAR DISORDER USING CONVERGENT FUNCTIONAL GENOMICS, Alexander Niculescu
5. MINOR ALLELE OF RS2230912 IS PROTECTIVE AGAINST RAPID CYCLING IN A SWEDISH SAMPLE OF BIPOLAR DISORDER PATIENTS, Pernilla Nikamo

O11: Early Career Investigator – Whole-Genome Approaches (Salon H)
Chair: Tiffany Greenwood, Co-Chair: Dan Rujescu

1. ADDRESSING ALLELIC HETEROGENEITY IN THE WHOLE-GENOME STUDY ERA: A POPULATION-BASED LINKAGE STUDY INVESTIGATING UNIPOLAR DEPRESSION, Sarah Cohen-Woods
2. IMPROVEMENT OF PHENOTYPING IN GENOME WIDE ASSOCIATION STUDIES ON SCHIZOPHRENIA: AN APPLICATION OF FACTOR ANALYSIS, Eske Derks
3. HIGH COVERAGE WHOLE-GENOME SEQUENCING IN SCHIZOPHRENIA: PROOF OF FEASIBILITY AND VARIANT ANNOTATION PROTOCOLS, Anna Need
4. GENETICS OF ALCOHOL DEPENDENCE COMORBIDITY IN BIPOLAR DISORDER: GENOME-WIDE ASSOCIATION STUDY, Evaristus Nwulia
5. GENE BASED AND PATHWAY ANALYSIS REVEAL GENOME-WIDE SIGNIFICANT GENES AND MOLECULAR PATHWAYS ASSOCIATED WITH BIPOLAR DISORDER, Inti Pedroso
6. A GENOME-WIDE ASSOCIATION STUDY OF OBSESSIVE-COMPULSIVE DISORDER USING DNA POOLING, Jens Wendland

1. FOLLOW-UP FINE MAPPING AND DEEP RE-SEQUENCING OF ZNF804A IN SCHIZOPHRENIA, Hywel Williams
2. SCHIZOPHRENIA-RELATED BEHAVIORAL CHANGES IN G72/G30 TRANSGENIC MICE, David-Marian Otte
3. DEEP RESEQUENCING AND ASSOCIATION ANALYSIS OF SCHIZOPHRENIA CANDIDATE GENES, James Crowley
4. FINE MAPPING OF AHI1 ON 6Q23 AS A SUSCEPTIBILITY GENE FOR SCHIZOPHRENIA FROM ASSOCIATION TO EVOLUTIONARY EVIDENCES, Federica Torri
5. COPY NUMBER VARIANTS AFFECTING MYELIN GENES IN SCHIZOPHRENIA, Lyudmila Georgieva

O13: Autism (Salon G)
Chair: Hiroshi Yoneda, Co-Chair: Homero Vallada

1. ALTERED SYNAPTIC PLASTICITY IN MICE LACKING ONE COPY OF THE SHANK3 GENE, A GENE MUTATED IN AUTISM SPECTRUM DISORDERS, Joseph Buxbaum
2. NARROWING THE CRITICAL DELETION REGION FOR AUTISM SPECTRUM DISORDERS IN CHROMOSOME 16P11.2, An Crepel
3. GENETIC MAPPING OF TEMPORAL MEMORY COMPONENTS IN MICE REVEALS A HOMOLOGOUS AUTISM LOCUS, Hilgo Bruining
4. DISSECTING THE CLINICAL HETEROGENEITY OF AUTISM SPECTRUM DISORDERS THROUGH DEFINED GENOTYPES, Hilgo Bruining
5. THE EFFECT OF CHR16P11.2 MICRODELETIONS AND MICRODUPLICATIONS ON GENE EXPRESSION IN AUTISM SPECTRUM DISORDERS AND SCHIZOPHRENIA, Mary Kusenda

O14: Epigenetics (Salon H)
Chair: Cathy Barr, Co-Chair: James Kennedy

1. INVESTIGATING GENOME-WIDE EPIGENETIC DIFFERENCES IN TWINS DISCORDANT FOR ALCOHOL DEPENDENCE, Charlotte Nymberg
2. IDENTIFICATION OF IMPRINTED GENES CONTRIBUTING TO SPECIFIC BRAIN REGIONS USING HIGH THROUGHPUT SEQUENCING, Cathy Barr
3. EPIGENETIC DYSREGULATION OF HTR2A IN POST-MORTEM BRAIN OF PATIENTS WITH SCHIZOPHRENIA AND BIPOLAR DISORDER, Hamid Mostafavi-Abdolmaleky
4. ALLELIC SKEWING OF DNA METHYLATION IS WIDESPREAD ACROSS THE GENOME, Jonathan Mill

O15: Gene Environment Interactions (Salon F)
Chair: Sibylle Schwab, Co-Chair: James Potash

1. THE INTERACTION OF VARIATIONS IN THE FKBP5 GENE AND ADVERSE LIFE EVENTS IN PREDICTING THE FIRST ONSET OF DEPRESSION DURING A TEN-YEAR FOLLOW-UP, Petra Zimmermann
2. INTERACTION BETWEEN CHILDHOOD ADVERSITY AND COMT VAL158MET POLYMORPHISM IN PSYCHOTIC DISORDER, Helen Fisher
3. PROMISES AND CHALLENGES OF COPY NUMBER VARIANTS IN AUTISM SPECTRUM DISORDERS AND SCHIZOPHRENIA, Alison Merikangas
4. SEARCHING FOR GENES WITH ENVIRONMENTAL INTERACTION IN COMPLEX DISORDERS, Kathleen Ries Merikangas

O16: Alcohol & Substance Abuse (Salon G)
Chair: Michael Owen, Co-Chair: Kenneth Kendler

1. ASSOCIATION OF SUBSTANCE USE DISORDERS WITH CHILDHOOD TRAUMA BUT NOT AFRICAN GENETIC HERITAGE IN AN AFRICAN AMERICAN COHORT, Francesca Ducci
2. ASSOCIATIONS OF DRD1-D5, SLC18A2, SLC6A3, DDC, AND TH WITH ALCOHOL DEPENDENCE (AD) AND RELATED DISORDERS IN THE IRISH AFFECTED SIB PAIR STUDY OF ALCOHOL DEPENDENCE (IASPSAD), Laura Hack
3. SPECIFIC AND NON-SPECIFIC GENETIC RISK FACTORS FOR ALCOHOL USE: ANALYSES OF DEVELOPMENTAL TRENDS AND GENE-ENVIRONMENT INTERACTIONS, Kenneth Kendler
4. RESEQUENCING OF NICOTINIC RECEPTOR GENES AND ANALYSIS OF RARE AND COMMON VARIATIONS WITH NICOTINE DEPENDENCE, Jennifer Wessel

O17: Dementia and Memory (Salon H)
Chair: Katherine Burdick, Co-Chair: Cathy Barr

1. GENOME-WIDE ASSOCIATION STUDY OF ALZHEIMER'S DISEASE, Denise Harold
2. IMPACT OF ALCOHOL ABUSE ON ALZHEIMER DISEASE, Michael Slifer
3. CNV GWAS FINDS RARE DELETIONS IN THYROID HORMONE GENE ASSOCIATED WITH ALZHEIMER’S DISEASE, Christophe Lambert
4. COMMON VARIANTS ASSOCIATED WITH BRAIN ATROPHY IN ALZHEIMER'S DISEASE PATIENTS, Simon Furney