P1.1: NEURONAL PLASTICITY AND NEURONAL DIVERSITY, Fred H. Gage

S1: Antidepressant Pharmacogenetics: GWAS and Beyond (Salon F)
Chair: Steven Hamilton

1. COMPARATIVE PHARMACOGENOMICS OF SEROTONERGIC AND NORADRENERGIC ANTIDEPRESSANTS: A GENOME-WIDE ANALYSIS OF THE GENDEP SAMPLE, Rudolf Uher
2. A GENOME-WIDE ASSOCIATION STUDY OF CITALOPRAM RESPONSE IN THE STAR*D SAMPLE, Steven Hamilton
3. A GENOMEWIDE ASSOCIATION STUDY POINTS TO MULTIPLE LOCI THAT PREDICT ANTIDEPRESSANT DRUG TREATMENT OUTCOME IN DEPRESSION, Susanne Lucae
4. TOWARDS POPULATION-BASED ANTIDEPRESSANT PHARMACOGENOMICS, Roy Perlis

S2: DNA Methylation in Human Brain and Neuropsychiatric Diseases (Salon G)
Chair: Chun-Yu Liu

1. COMPREHENSIVE DNA METHYLATION ANALYSIS IN NEURONS AND NON-NEURONS FROM HUMAN POSTMORTEM BRAINS AND ITS APPLICATION TO MENTAL DISORDERS, Tadafumi Kato
2. DNA METHYLATION SIGNATURES WITHIN THE MAJOR DEPRESSIVE DISORDER BRAIN, James Potash
3. QTLS FOR GENE-SPECIFIC METHYLATION IN HUMAN BRAIN, Dandan Zhang
4. REGULATION AND FUNCTION OF CPG METHYLATION AND DNA METHYLTRANSFERASES IN POST-MITOTIC NEURONS, Rajiv Sharma
5. CORRELATIONS BETWEEN GENE EXPRESSION AND DNA METHYLATION IN HUMAN BRAIN, Chao Chen

S3: Risk Variants Through Biology to Treatment: Mapping the Challenges and the Potential (Salon H)
Chair: Michael Gill, Co-Chair: Aiden Corvin

1. DELINEATING THE EFFECT ON SZ OF GWAS IDENTIFIED RISK ALLELES BASED ON NEUROPSYCHOLOGICAL PERFORMANCE, Gary Donohoe
2. THE EFFECTS OF RISK VARIANTS ON BRAIN STRUCTURE, FUNCTION AND CONNECTIVITY, Andrew McIntosh
3. MUTANT MOUSE MODELS: PSYCHOPATHOLOGY AND TRANSLATIONAL PSYCHOPHARMACOLOGY, John Waddington
4. SCHIZOPHRENIA PATHOGENESIS: INSIGHTS FROM ETIOLOGICALLY VALID MOUSE MODELS OF RARE DISEASE VARIANTS, Joseph A. Gogos
5. ESTABLISHMENT OF A METHOD FOR HIGH-THROUGHPUT FUNCTIONAL SCREENING OF PATIENT REGULATORY & CODING VARIANTS IN MICE, Elizabeth M. Simpson
6. PROMOTION OF SYNAPTIC AND CIRCUIT MATURATION PARTIALLY REVERSES SYMPTOMS IN A MOUSE MODEL OF RETT SYNDROME, Daniela Tropea

Lunch (Salon D, E)

O1: Mood Disorders 1 (Salon F)
Chair: John Nurnberger, Co-Chair: Melvin McInnis

1. SUPPORT FOR A BIPOLAR AFFECTIVE DISORDER SUSCEPTIBILITY LOCUS ON CHROMOSOME 12Q24.3, Leslie Foldager
2. PER2 VARIATION IS ASSOCIATED WITH DEPRESSION VULNERABILITY, Catharina Lavebratt
3. GENOME WIDE ASSOCIATION SCAN OF SUICIDALITY IN MAJOR DEPRESSION, Alexandra Schosser
4. EXPLORATION OF THE GENETIC DIFFERENCES BETWEEN MONOZYGOTIC TWINZ DISCORDANT FOR BIPOLAR DISORDER, Hiroko Sugawara
5. SYSTEMATIC ANALYSIS OF CIRCADIAN GENES IN A POPULATION-BASED SAMPLE REVEALS ASSOCIATION OF TIMELESS TO DEPRESSION AND SLEEP DISTURBANCE, Tiina Paunio
6. PI3K/AKT SIGNALING IN DOPAMINERGIC ACTION, Thomas Franke
7. TPH2 RISK HAPLOTYPE ASSOCIATED WITH IMPULSIVE AGGRESSION IN BORDERLINE PERSONALITY DISORDER, Larry Siever

1. WHOLE-GENOME ASSOCIATION STUDY OF RESPONSE TO LITHIUM TREATMENT IN BIPOLAR DISORDER, Alexandra Dedman
2. MOLECULAR NETWORKS OF LITHIUM RESPONSE: CONVERGENCE ACROSS PHYLOGENY, Sevilla Detera-Wadleigh
3. BEHAVIORAL ANALYSES OF TRANSGENIC MICE HARBORING BIPOLAR DISORDER CANDIDATE GENES, IMPA1 AND IMPA2, Takeo Yoshikawa
4. CANDIDATE GENE PHARMACOGENETICS STUDY OF MGLU 2/3 AGONIST LY2140023,
   AnnCatherine Downing
5. CONVERGENT ANIMAL AND HUMAN EVIDENCE FOR A ROLE OF PPM1A GENE IN RESPONSE TO ANTIDEPRESSANTS, Karim Malki
6. INDIVIDUALIZED ANTIPSYCHOTIC THERAPY FOR SCHIZOPHRENIA, Karolina Aberg

1. THE SYMPTOMATIC PROFILE OF PANIC DISORDER IS SHAPED BY THE 5-HTTLPR POLYMORPHISM, Martin Schalling
2. POLYMORPHISMS IN THE GENE ENCODING THE NEUROPEPTIDE GALANIN ARE ASSOCIATED WITH HPA-AXIS DYSREGULATION AND SYMPTOME SEVERITY IN MAJOR-DEPRESSIVE- AND ANXIETY-DISORDER PATIENTS, Paul G. Unschuld
3. VARIANTS IN SLITRK1 ARE ASSOCIATED WITH THE OBSESSIVE-COMPULSIVE DISORDER SPECTRUM, Uzoezi Ozomaro
4. ACCELERATED TELOMERE SHORTENING IN A POPULATION-BASED NESTED CASE-CONTROL STUDY OF ANXIETY DISORDER PATIENTS, Iiris Hovatta
5. PRIORITIZATION AND ASSOCIATION ANALYSIS OF MURINE-DERIVED CANDIDATE GENES IN ANXIETY-SPECTRUM DISORDERS, John Hettema

1. HAPLOTYPE SEGREGATION IN MULTIPLEX ADHD FAMILIES AT DIFFERENT CHROMOSOMAL LOCI, Michelle Lin
2. A NEURODEVELOPMENTAL PATHWAY FOR ATTENTION DEFICIT HYPERACTIVITY DISORDER (ADHD): INTEGRATING THE GENOME-WIDE ASSOCIATION FINDINGS, Barbara Franke
3. RISK PATHWAYS OR PLEIOTROPIC EFFECTS? AN INVESTIGATION INTO COGNITIVE INTERMEDIATE PHENOTYPES CONTRIBUTING TO THE ASSOCIATION BETWEEN COMT VAL158MET GENOTYPE AND ANTISOCIAL BEHAVIOUR IN CHILDREN WITH ADHD, Kate Langley
4. EVIDENCE THAT RARE STRUCTURAL VARIANTS ARE ASSOCIATED WITH ATTENTION-DEFICIT HYPERACTIVITY DISORDER AND OVERLAP WITH AUTISM SUSCEPTIBILITY LOCI, Nigel Williams

O5: Genetic Overlap (Salon G)
Chair: Nick Craddock, Co-Chair: Jordan Smoller

1. COPY NUMBER VARIATION AND GENE DOSAGE CHANGES IN AUTISM: OVERLAP WITH REGIONS INVOLVED IN SCHIZOPHRENIA AND BIPOLAR DISEASE, Moyra Smith
2. ABCA13: A CANDIDATE GENE FOR SCHIZOPHRENIA AND BIPOLAR DISORDER, Douglas Blackwood
3. RARE COPY NUMBER VARIANTS: A POINT OF RARITY IN GENETIC RISK FOR BIPOLAR DISORDER AND SCHIZOPHRENIA? Detelina Grozeva
4. BETA-CATENIN PROMOTER CHIP-CHIP REVEALS POTENTIAL SCHIZOPHRENIA AND BIPOLAR DISORDER GENE NETWORK, Herb Lachman
5. WHOLE-GENOME ANALYSIS REVEALS AN OVERLAPPING GENETIC BASIS FOR BIPOLAR DISORDER, MAJOR DEPRESSION, AND SCHIZOPHRENIA, Thomas G. Schulze

O6: Schizophrenia 1 (Salon H)
Chair: Pamela Sklar, Co-Chair: Lin He

1. DUPLICATION AND DELETION AT 15Q11.2 ARE ASSOCIATED WITH SCHIZOPHRENIA, YongYong Shi
2. STRUCTURAL IMAGING REVEALS NOVEL GENETIC INFLUENCES IN SCHIZOPHRENIA, Jessica Turner
3. CLINICAL AND COGNITIVE ASSOCIATIONS AND DATA MINING EVIDENCE OF EPISTASIS IN THE NIMH/GCAP GWA STUDY, Richard Straub
4. ASSOCIATION OF THE DISOCIDIN DOMIAN RECEPTOR 1 WITH POSITIVE SYMPTOMATOLOGY IN SCHIZOPHRENIC PATIENTS, Elisabet Vilella
5. ASSOCIATION OF 5HT2C RECEPTOR POLYMORPHISMS WITH PSYCHOPATHOLOGY AND TREATMENT RESPONSE IN SCHIZOPHRENIA, Herbert Meltzer
6. COPY NUMBER VARIATIONS OF SCHIZOPHRENIA SUSCEPTIBILITY LOCI ARE ASSOCIATED WITH A SPECTRUM OF SPEECH AND DEVELOPMENTAL DELAYS AND BEHAVIOR PROBLEMS, Trilochan Sahoo