UC San Diego School of Medicine, Continuing Medical Education
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Dear Colleague:

We have an exciting program for 2014! This year, we have responded to your comments following our 2012 conference. We no longer have two tracks, therefore no one risks missing a talk. There are three major themes: Prevention, Innovative Care, and Clinical Care. The Robert Katzman Memorial Lecture will honor our first Director and his work in Epidemiology and the Leon Thal Memorial Lecture will honor our second Director and his work in AD therapeutics.

Prevention is a major current focus in AD research and six talks will address this theme. Kristine Yaffe, MD, from UCSF opens our conference with the rationale for the study of prevention. She is followed by two of our UCSD researchers, Drs. Salmon and Galasko, who discuss cognitive and biomarker tools for use in studies of prevention. Dr. Yaffe then returns to discuss changes in one’s lifestyle that might impact the onset of AD. This leads to a discussion of prevention clinical trials by UCSD’s Dr. Paul Aisen. Ken Langa, MD, presents the Robert Katzman Memorial Lecture, “The Changing Risk of Dementia in the Population: Are we already preventing it?” This focuses on recent evidence suggesting that the prevalence of AD may be declining, which is welcome but controversial news.

The afternoon of the first day will focus on innovative care. Katie Maslow, MSW, will discuss management of dementia patients in hospital settings. Poor staff awareness or limited dementia documentation during hospitalization places patients with dementia at greater risk for negative outcomes. Innovations in end-of-life care will be presented by Maribeth Gallagher, DNP, a psychiatric nurse practitioner from Hospice of the Valley in Phoenix. Dr. Joshua Grill from UCLA, discusses the neuroscience of music in dementia and an innovative intervention using personalized music with dementia residents in long-term care. Finally, an overview of the use of technology in the evaluation and care of AD patients brings us novel management ideas for caregivers and health care providers.

On day two, we begin with the Leon Thal Memorial Lecture given by Dr. Randall Bateman of Washington University. He will discuss what we have learned in the study of early-onset familial AD. This is followed by an update by one of our young faculty researchers, Clotilde Lagier-Tourenne, who studies the heterogeneous group of Frontal Temporal Dementias (FTD).

A series of discussions on clinical care are designed to give you up-to-date and applied knowledge relevant to community practice. Dr. Jody Corey-Bloom will lead expert clinicians who will review dementia case studies that address: when to order neuroimaging; vascular factors and cognitive impairment; and sleep assessment and management. Dr. Dan Sewell, in the UCSD Department of Psychiatry, will provide an overview of pharmacological behavior management.

Dementia is viewed differently around the world, however stigma associated with a dementia diagnosis is cross-cultural. In 2012, Alzheimer’s Disease International generated a report, “Overcoming the Stigma of Dementia;” one of the authors of the report will present these illuminating findings. Dr. Jason Karlawish from University of Pennsylvania will follow with a discussion on the ethical issues surrounding prevention studies in AD.

Objectives

At the end of the course, conference participants should be able to:

  • Describe the rationale for the study of prevention of Alzheimer's disease and possible lifestyle interventions.
  • Discuss several current methods to detect preclinical changes in the brain that might predict future onset of Alzheimer's disease.
  • Answer the question: "Are we already preventing Alzheimer's disease?"
  • Communicate the importance of having a dementia diagnosis in the hospital record when a person is admitted.
  • Describe several innovative end of life care practices.
  • Discuss what has been learned by the study of early-onset familial Alzheimer's disease that has helped us understand the biology of the disease.
  • Describe how different cultures around the world perceive dementia and the stigma that is often associated with it.
  • Describe how a community physician would make the decision to order brain imaging studies for a possible dementia patient.
  • Discuss how sleep changes in aging and dementia.
  • Describe how medications can be used to manage behavioral symptoms in dementia.

Target Audience

Physicians, researchers, nurses, nurse practitioners, neuropsychologists, physician assistants, residential care and nursing home administrators, social workers and pharmacists.

About the UC San Diego Shiley-Marcos Alzheimer's Disease Research Center

The Shiley-Marcos Alzheimer’s Disease Research Center (ADRC) was established in 1984 as one of the original five Alzheimer’s Disease Centers supported by the National Institute on Aging, a branch of the National Institutes of Health.

Under the direction of Robert Katzman, MD, a number of scientists and scholars renowned for their work in Alzheimer’s disease and aging assembled at UCSD to conduct investigations into the etiology and effects of this devastating disease. Working with multiple facilities around the country, our clinicians and basic researchers have been instrumental in helping the scientific community understand the clinical presentation and the basic biology of the disease. Our clinical studies have also uncovered information that has led to the development of therapies that help slow the progression of the disease and, in some cases, improve memory.

The center’s clinical research program enrolls both people with Alzheimer’s disease and related dementias, as well as control subjects. Since its inception, more than 2,000 volunteers have participated in our research studies, including more than 300 participants in our Hispanic program.

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UC San Diego School of Medicine, Continuing Medical Education• 2251 San Diego Ave., A-160 • San Diego, CA 92110-2981
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