UC San Diego School of Medicine, Continuing Medical Education
(858) 534-3940 | ocme@ucsd.edu | cme.ucsd.edu

BACKGROUND

From the beginning, these courses, were not designed as discussions of specific therapies or diagnoses, but rather to address fundamental issues such as the pathophysiology of pain and the mechanism of action, pharmacokinetics and pharmacodynamics of pain therapeutics. The first two courses held were devoted to a detailed review and discussion of pain mechanisms. The first course in 2007  (72 attendees pictured below) from  as  far away as Japan, Australia and New Zealand,  detailed the basic physiology and pathophysiology of pain pathways. The 2012 course(113 attendees)  reviewed the mechanisms underlying pain processing in a variety of clinically-defined pain states (cancer, visceral inflammation,post-tissue injuryand post-nerve injury) and a mechanistic review of pain therapeutics. In 2016 the course (142 attendees)  focused on complex systems and addressed issues such asthe evolution of consciousness, development of facilitated pain states anddevelopment of validated veterinary pain models. The focus for 2016 is on the mechanisms of actions of analgesics, with a novel focus on the development of new therapeutics and the use of veterinary clinical pain models as well as validated inventories in the development of veterinary analgesics. Invitedspeakers have been  selected fromacademia, private veterinary practice and companies with analgesics in clinical development for veterinary use. In each case, speakers will present a detailedand critical review of theapproaches employed to evaluate efficacyand target engagement. Speakers from the US FDA Center for Veterinary Medicine will lecture on the processes and regulatory requirements for the development and use of analgesic therapiesin “small” and “large” animals. This will be a very high level meeting with significant content relevant to basic issues related to  pain  in the veterinary patient  and the development of novel therapeutics.Each lecture will be followed by ample time for a question and answer period.

As a follow up, we are pursuing the participation of a high profile veterinary journal  in which to publish an overview of the symposium, viz pain therapeutics  in veterinary medicine and the road map for the development of veterinary analgesics.