UC San Diego School of Medicine, Continuing Medical Education
(858) 534-3940 | ocme@ucsd.edu | cme.ucsd.edu

Faculty

Tony Yaksh, PhD
Course Organizer
Distinguished Professor of Anesthesiology and Pharmacology
University of California, San Diego
La Jolla, CA

Dr. Yaksh joined UCSD in 1988 as Professor and Vice Chairman for Research in the Department of Anesthesiology and Professor of Pharmacology. Dr. Yaksh's research interests are primarily in the area of the biology of pain processing, with a particular interest in the role of non-neuronal cells and lipid mediators in pain transmission. He is an expert on issues related to spinal drug kinetics and the evaluation of the safety of spinally delivered agents. He has published more than 800 papers with 46,000 citations in >26,000 papers and edited 6 texts and is working on a 7th. He has been a mentor to more than 150 post-graduate Fellows. He has been funded consistently by the NIH since 1977 and has twice been a Jacob Javitz award recipient. He is currently the Principal Investigator on several NIH grants and numerous contracts. He has received honors and awards, including the FWL Kerr award of the American Pain Society, the American Society of Anesthesiology (ASA) Award for Excellence in Research, the Rovenstein award from the New York Society of Anesthesiology, and the Torsten Gordh award from the Swedish Society of Medicine.

William Muir, DVM, PhD, DACVAA, DACVECC
Course Organizer
Senior Consultant 
Q Test Labs
Columbus, Ohio

Dr. Muir served as Professor and Director of Anesthesiology and Pain Management at The Ohio State University College of Veterinary Medicine (1970-2007), as the research director for the US based Research Medications and Testing Consortium (RMTC) for 2 years (2007-2009), and as the Chief Medical Officer for the Animal Medical Center in New York City (2009-2012). He currently is a Professor of physiology in the College of Veterinary Medicine at Lincoln Memorial University in Harrogate TN, and Scientific Advisor for QTest laboratories (preclinical research facility) in Columbus OH.

Michael T. Alkire, MD
Long Beach VA Healthcare system
Chief of Anesthesiology Service
Department of Anesthesiology and Perioperative Care
Center for the Neurobiology of Learning and Memory
University of California, Irvine 
Irvine, CA

Dr. Alkire is Professor of Anesthesia at UC Irvine and Chief of Anesthesia at the Long Beach VA. His research focuses on mechanisms of anesthetic action on consciousness, memory and pain processing. He received his medical degree from the University of California, Los Angeles in 1990 and subsequently completed anesthesia residency at the University of California, Irvine where he has continued his clinical career. He uses neuroimaging technologies such as positron emission tomography (PET), functional magnetic resonance imaging (fMRI) and high-density electroencephalography (EEG), as well as small animal experimentation, to identify and experimentally manipulate various key sites of anesthetic action in the brain. Dr. Alkire is also interested in the investigation and development of new clinical monitoring technology and has recently become a proponent of using stellate ganglion blocks for the treatment of post traumatic stress disorder in America’s Veterans. .

Booth

Dawn M. Boothe, DVM, MS, PhD
Professor of Physiology and Pharmacology
Department of Anatomy, Physiology and Pharmacology
Director, Clinical Pharmacology Laboratory
Auburn University College of Veterinary Medicine
Auburn, AL

Dr. Boothe joined the Auburn University College of Veterinary Medicine in 2003. She received her B.S. degrees in Zoology (1977) and Veterinary Medicine (1978), D.V.M. degree (1980), and M.S. degree in Physiology (1986) from Texas A&M University. She continued her education with an internship in 1981 at Auburn University’s Small Animal Surgery and Medicine, then went back to Texas A&M University, Small Animal Internal Medicine for her residency program in 1985. Dr. Boothe completed her Ph.D. degree and fellowship in 1989 in the field of Physiology (Clinical Pharmacology) at Texas A&M University. Dr. Boothe is a Diplomate ACVIM (Internal Medicine) and Diplomate ACVCP (Clinical Pharmacology). Dr. Booth has received the Distinguished Achievement Award in Teaching (University Level), May 1997, and the Merck AgVet Award for Creativity in Teaching, July 1996, at Texas A&M University. Currently, Dr. Booth is assisting in teaching Veterinary Pharmacology to second-year veterinary students and is the Director of the Clinical Pharmacology Laboratory at the Auburn University College of Veterinary Medicine.

Dorothy (Dottie) Cimino Brown MS, DVM, DACVS
Senior Research Advisor
Translational Comparative Medical Research (TCMR)
Eli Lilly/Elanco

Greenfield, IN

Dottie is the lead executional scientist for TCMR at Eli Lilly/Elanco. TCMR facilitates companion animal clinical trials designed to inform assets in the Lilly pipeline, as well as assets of potential Lilly partners. Dottie came to Elanco from the School of Veterinary Medicine at the University of Pennsylvania, where she served as Professor of Surgery and led a successful sponsored translational research program that focused on the measurement and management of chronic pain in companion animals. She developed and validated a series of outcome assessment instruments for chronic pain and then applied those instruments to clinical trials evaluating the efficacy of novel interventions, such as targeted neurotoxins. Dottie continues studies on the refinement and validation of outcome assessment instruments for companion animal clinical trials as well as identifying predictors for placebo and treatment responders in analgesic trials. Dottie received her Master’s in clinical epidemiology and biostatistics from the clinical trials program at the School of Medicine at Penn. She built and directed the Veterinary Clinical Investigation Center there, which provided the expertise and infrastructure for the design, implementation, and analysis of high quality veterinary clinical trials in a wide variety of target populations. At Eli Lilly/Elanco, she now directs studies across institutions in order to leverage high quality, systematic translational data with the goal of improving both human and animal health.

Hans Coetzee, BVSc, Cert CHP, PhD, Diplomate ACVCP
Professor and Head
Department of Anatomy and Physiology
Kansas State University
Manhattan, KS

Dr. Hans Coetzee is a Professor and Head of the Department of Anatomy and Physiology at Kansas State University. He was awarded his Bachelor of Veterinary Science degree from the University of Pretoria, South Africa in 1996. After graduation he worked for four years in mixed animal practice in Northern Ireland followed by 2 years in pharmaceutical research and development at Norbrook Laboratories Ltd. He earned a specialist Certificate in Cattle Health and Production from the Royal College of Veterinary Surgeons (London) in 2000 and a doctorate in Veterinary Microbiology from Iowa State University in 2005. He holds dual board certification in the American College of Veterinary Clinical Pharmacology and American College of Animal Welfare and is a European Specialist in Animal Welfare Science, Ethics and Law. His professional interests include the development of pain assessment techniques and practical analgesic drug regimens for use in food animals. He has published 130 peer-reviewed scientific papers and received over $10 million in research funding. In his free time he enjoys spending time with his wife and his twin daughters.

C.A. Tony Buffington, DVM, PhD
Department of Medicine and Epidemiology
UC Davis School of Veterinary Medicine
Davis, CA

Dr. Tony Buffington is an emeritus professor of veterinary clinical sciences at The Ohio State University College of Veterinary Medicine and a clinical professor (volunteer) at the UC Davis School of Veterinary Medicine. He received bachelors, masters and PhD degrees in nutrition and the Doctor of Veterinary Medicine degree from UC Davis, and was board-certified in veterinary nutrition (now emeritus). His clinical interests include developmental origins of health and disease, stress effects on disease, obesity, evidence- based medicine, and effective medical communications. His research has documented the effects of environmental stressors on disease in cats, and the role of effective environmental enrichment in mitigating them to promote recovery.

Earl Carstens, PhD
Distinguished Professor
Department of Neurobiology, Physiology, and Behavior
University of California, Davis
Davis, CA

Dr. Carstens is Distinguished Professor of Neurobiology, Physiology and Behavior at the University of California, Davis. He completed his PhD in neurobiology at the University of North Carolina. Dr. Carsten's laboratory investigates the neural mechanisms of oral and cutaneous chemical irritation, pain, itch and temperature sensation. His laboratory employs behavioral, neurophysiological, neuroanatomical and cellular approaches to address the question of whether or not itch and pain sensations are conveyed by separate neural pathways and how these sensory qualities interact. Of particular interest is the ability of several itch mediators (proteases, serotonin, histamine) to elicit prolonged scratching behavior in rodents and excitation of superficial spinal dorsal horn neurons over comparable time courses.

Bernd Driessen, DVM, PhD
Section of Anesthesia
Department of Clinical Studies
New Bolton Center, School of Veterinary Medicine
University of Pennsylvania
Philadelphia, PA
Managing Partner Narkovet Consulting®, LLC

Dr. Bernd Driessen is full professor at the School of Veterinary Medicine of the University of Pennsylvania. He received his DVM from Free University of Berlin in 1988 and completed his doctorate in neuropharmacology with a Dr. med. vet. degree (PhD equivalent) at the same university in 1991 after completing his experimental studies at the laboratories of Grünenthal Pharmaceuticals in Aachen, Germany. From 1991 to 1995 he held position of Assistant Professor of Pharmacology at the Albert-Ludwig’s University of Freiburg’s Medical School and obtained his board certification in pharmacology and toxicology from the German Veterinary Medical Association. In 1998, Bernd completed a residency in anesthesia & critical patient care at the University of California-Davis’ School of Veterinary Medicine. He is boarded with the European College of Veterinary Pharmacology & Toxicology and with the American College of Veterinary Anesthesia and Analgesia, and is currently teaching veterinary anesthesia and pharmacology at the University of Pennsylvania and the European School for Advanced Veterinary Studies in Europe and Asia. His research focuses on the development of and treatment with hemoglobin-based blood substitutes, techniques of loco-regional anesthesia & analgesia, pulmonary gas exchange during anesthesia, and the pharmacology of new anesthetic and analgesic drugs.

Steven M. Fox, DVM, MBA, PhD
President and CEO
Fox Third Bearing, Inc
Clive, IA

Dr. Fox received his MS and veterinary medical degrees from the University of Illinois, and MBA (entrepreneurialism and new ventures) and PhD (pain management) degrees from Massey University in New Zealand. Dr. Fox served on the faculty of the veterinary teaching hospital at Mississippi State University, as product manager at Pioneer Hi-Bred International, senior lecturer in companion animal orthopedic surgery at Massey University, senior veterinary specialist at Pfizer Animal Health, and Director of Pain Management at Novartis Animal Health. Dr. Fox is an adjunct assistant professor at the University of Illinois, as well as adjunct associate professor at Massey University, advisor to the University of Tennessee Pain Center, founding member of the Companion Animal Pain Management Consortium Leadership Council, and Fellow of the New Zealand Institute of Management as well as an Educational Manager for the Western Veterinary Conference.

He has authored more than 80 professional publications, 2 textbooks, 5 textbook chapters and 2 interactive CD/DVDs.

Alonso Guedes, DVM, MS, PhD, Diplomate ACVA
Associate Professor, Anesthesia and Pain Medicine Veterinary Clinical Sciences Department
College of Veterinary Medicine
University of Minnesota
Minneapolis, MN

Dr. Guedes was an Assistant Professor at the University of California, Davis (UC Davis), School of Veterinary Medicine and is currently Assistant Professor at the School of Veterinary Medicine at the University of Minnesota. He has been involved in understanding the mechanisms of laminitis and developing novel therapeutics for intervening in this pain state.

Patrick Mantyh, PhD
Professor Department of  Pharmacology
University of  Arizona
Tucson, AZ

Dr. Patrick Mantyh received his PhD in neuroscience from the University of California, San Francisco in 1981 and completed a postdoctoral fellowship in pharmacology at the University of Cambridge in 1983. Dr. Mantyh's lab developed the first rodent model of bone cancer pain in 1999 and then a model of bone fracture and orthopedic surgery pain in 2007. These models are now used by labs around the world. Dr. Mantyh’s lab pioneered the use of intrathecal Substance P-Saporin, targeting acidosis (Densumab &  bisphosphonates), and the use of anti-NGF antibodies and TrkA antagonists for the relief of skeletal pain. More recently, his focus has been to investigate the cellular and molecular mechanisms that regulate skeletal pain, bone remodeling and ectopic nerve sprouting in the bone and joint. The major goal of his lab is use these findings to develop novel therapies that reduce skeletal pain and promote skeletal health and successful aging.

Jason McDougall, PhD
Professor, Department of Pharmacology
Department of Anesthesia, Pain Management & Perioperative Medicine
Dalhousie University
Halifax, NS Canada

Prof. McDougall was born in South Shields and educated in Scotland. He received his PhD in Joint Physiology from the University of Glasgow and subsequently undertook postdoctoral training in Canada, Germany and Spain. Prof. McDougall was awarded postdoctoral fellowships from the Alberta Heritage Foundation for Medical Research (AHFMR), the Medical Research Council of Canada and was the recipient of the Ernst & Young Joint Injury & Arthritis Research Fellowship. In 2001, he joined the Faculty of Medicine at the University of Calgary where he held an AHFMR Senior Scholarship as well as an Arthritis Society Investigator award. He transferred to Dalhousie University in 2011 where he is currently a Professor of Pharmacology and Anaesthesia.

Prof. McDougall’s research focuses on the neurobiology of pain and inflammation in the development of arthritis. His research is currently examining the role of cannabinoids and proteinases in the control of arthritis pain and inflammation. His research goal is to identify novel drug targets and develop new treatments which will help alleviate chronic pain and resolve joint inflammation. He currently receives project funding from CIHR and The Arthritis Society of Canada. He has been a consultant for AstraZeneca (UK), Eli Lilly & Company (USA), Pfizer (UK), Pharmin (USA) and Antibe Pharmaceuticals (Canada). Prof. McDougall is an editor for Inflammation Research, Journal of Inflammation, and BMC Anaesthesiology as well as the Chair of the Scientific Advisory Committee at the Arthritis Society. He has also won numerous awards for his homebrewed beers which have been commercially produced.

Joanne R. Paul-Murphy, DVM
Professor
Professor in the Department of Medicine & Epidemiology
Chief of the Companion Avian and Exotic Pets Medicine Program
University of California, Davis School of Veterinary Medicine
Davis, CA

Dr. Paul-Murphy is board-certified through the American College of Zoological Medicine (1991) as well as the American College of Animal Welfare (2012) received her BS and DVM from Cornell University, followed by a Residency in zoological medicine at the University of California under Dr. Murray E. Fowler). Dr. Paul-Murphy then served as Chief of the Zoological Medicine Service at UC Davis before working as first an associate veterinarian and then Chief of Service at the California Primate Research Center. In 1991, Dr. Paul-Murphy moved to the University of Wisconsin-Madison where she worked at the Wisconsin Regional Primate Research Center. After 18 years at the University of Wisconsin, rising to the rank of Professor, Dr. Paul-Murphy moved to UC Davis in 2009 where she took her current position. In 2013, Dr. Paul-Murphy was the first person to be awarded in one year an annual research grant from the American Association of Zoo Veterinarians, the Association of Avian Veterinarians, and the Association of Exotic Small Mammal Veterinarians. Although her research interests focus on comparative analgesia and companion bird welfare, her contributions to the field of zoological medicine in general and avian medicine in particular are extensive in number and breadth of field.

Sam Ridgway, DVM, PhD, DACZM
National Marine Mammal Foundation   
San Diego, CA

Dr. Ridgway earned Bachelor of Science and Doctor of Veterinary Medicine degrees from Texas A&M University. He earned his PhD in neurobiology from the University of Cambridge in England. In the 1960’s, Dr. Ridgway pioneered dolphin anesthesia, medical technology, and methods for studying trained dolphins swimming freely in the open sea (his discoveries have been published in more than 275 papers in leading scientific journals such as Science, Nature, Journal of the Acoustical Society of America and Scientific American).

Dr. Ridgway is President of the National Marine Mammal Foundation. He is one of the founders of the Navy Marine Mammal Program starting in 1961 and has 52 years of experience in marine mammal medicine and research. He is often called the “father of marine mammal medicine” because of his development of dolphin anesthesia, medical technology, and discoveries aiding marine mammal care.

Jacky Reid, BVMS, PhD DVA, DipECVAA, MRCA, MRCVS
Honorary Senior Research Fellow
University of Glasgow
CEO NewMetrica Ltd.
Glasgow, UK

Having been awarded her PhD in 1984 for studies relating to the effects of mercury pollution on avian eggshells, Dr. Reid then specialised in veterinary anaesthesia, being awarded the RCVS Diploma in Veterinary Anaesthesia in 1988 and the Dipl ECVAA in 1995. In 1998 she became Professor of Anaesthesia in the University of Glasgow and was the recipient of the BSAVA Simon Award for outstanding contribution to veterinary surgery in 2016.

Dr. Reid co-founded the Glasgow University Pain and Welfare Group (recipient of the 2009 UFAW Welfare Award), whose work is focused on animal pain and health-related quality of life (HRQL) measurement.  The group developed the Glasgow Composite Measure Pain Scale (CMPS-SF) for acute pain in dogs and the CMPS – Feline for acute pain in cats. VetMetrica for dogs and VetMetrica for cats are owner completed web-based generic HRQL instruments which measure the impact of chronic pain and non-painful chronic disease on HRQL.  Current work is focused on a disease specific OA module for cats.

Dr. Reid retired from Glasgow Veterinary School in 2006 to concentrate full time on her research within the Pain and Welfare Group, having been Head of Anaesthesia until 2004 and Associate Dean for Clinical services 2004 - 2006. She is currently an Honorary Senior Research Fellow in the University of Glasgow and a director in NewMetrica a company specialising in developing valid, reliable and responsive instruments to measure pain and HRQL in non-verbal species.

Kurt K. Sladky, MS, DVM, Dipl. ACZM, Dipl. ECZM
School of Veterinary Medicine
Department of Surgical Sciences
University of Wisconsin
Madison, WI

Dr. Sladky received his MS and DVM degrees from the University of Wisconsin, and completed a Residency in Zoological Medicine at North Carolina State University College of Veterinary Medicine. He is a Diplomate of the American College of Zoological Medicine and the European College of Zoological Medicine (Herpetology & Zoo Health Management). He is Clinical Professor of Zoological Medicine, Special Species Health at the University of Wisconsin-Madison School of Veterinary Medicine, and a faculty member of the Master’s of Public Health Program, University of Wisconsin-Madison School of Medicine and Public Health. His clinical responsibilities include: medical and surgical management of pet nondomestic, zoo, and wildlife species.  His clinical research encompasses comparative studies in nondomestic animal analgesia and anesthesia, with an emphasis on analgesic efficacy in reptiles, amphibians, and fish species. From a theoretical perspective, he is interested in the evolution of nociception. His other research interests focus on the anthropogenic influences on infectious and noninfectious diseases affecting free-ranging wildlife species, and the consequences on ecosystem, animal, and human health.

W. Daniel Tracey, Jr, PhD
Professor Department of Biology
Indiana University
Bloomington, IN

Dr. Tracey received his BA at SUNY Buffalo in 1991; his MS at Florida International University in 1994; and his PhD at SUNY Stony Brook in 1999. He was a postdoctoral Fellow, California Institute of Technology, 1999-2004. Research in the Tracey laboratory aims to understand general principles that govern the specification and function of neuronal circuits. They study this problem using the fruit fly Drosophila melanogaster whose relatively simplified nervous system must perform many of the same computations that are carried out by higher species. Despite its simplified brain, Drosophila perform an array of complex behaviors. Powerful genetic tools of Drosophila enable the dissection of neural circuits with a precision that is not matched in any other model system. Genetically encoded calcium sensors measure neuronal activity of identified neurons while neuronal silencers and activators allow determination of the behavioral consequences of the same activity. Optogenetic tools allow activation of behaviors via remote control by simply shining light on the animals. The primary focus is to use the fly model to identify circuits and genes that function in nociception. These studies lead to a greater understanding of pain signaling.

Edgar T. Walters, PhD
Professor
Department of Integrative Biology and Pharmacology
University of Texas
Houston, TX

The research of Dr. Walters has revealed striking similarities in how nociceptors of invertebrates and vertebrates detect and “remember” injury-related stimulation. Mollusks offer well-known advantages for relating properties of identifiable cells to behavioral functions. Using the large marine snail, Aplysia, to define cellular signaling pathways demonstrates systems for the induction and long-term maintenance of hyper-excitability in the cell body, axon, and peripheral and central terminals of identified nociceptors. Some of these signals also contribute to long-term alterations in vertebrate nociceptors. Others have not yet been investigated in vertebrates, such as a potent pathway that depends upon local depolarization (and protein synthesis) but not calcium signals. In recent work, another mollusc, the longfin Atlantic squid, displays long-term nociceptive sensitization of defensive behavior paralleled by sensitization of the peripheral branches of nociceptors. Comparisons of behavioral alterations and nociceptor memory in squid, Aplysia, and rats point to shared functions that have shaped the evolution of nociceptor plasticity and to conserved mechanisms that may be fundamental to many memory-like phenomena, including some forms of chronic pain.

Maureen Helinski Clarke, CMP
Organizing Committee
Program Manager
Continuing Medical Education

UC San Diego School of Medicine
La Jolla, CA
  Chris Radewicz
Organizing Committee
Administrative Assistant
Department of Anesthesiology
UC San Diego School of Medicine
La Jolla, CA